| Date | Artist - Title | Weeks at #1 |
|---|---|---|
2006 Number One Songs | ||
| – | Shayne Ward - That's My Goal | 4 |
| – | Arctic Monkeys - When The Sun Goes Down | 1 |
| – | Notorious B.I.G. feat. Diddy, Nelly, Jagged Edge and Avery Storm - Nasty Girl | 2 |
| – | Meck feat. Leo Sayer - Thunder In My Heart Again | 2 |
| – | Madonna - Sorry | 1 |
| – | Chico - It's Chico Time | 2 |
| – | Orson - No Tomorrow | 1 |
| – | Ne-Yo - So Sick | 1 |
| – | Gnarls Barkley - Crazy | 9 |
| – | Sandi Thom - I Wish I Was A Punk Rocker (With Flowers In My Hair) | 1 |
| – | Nelly Furtado - Maneater | 3 |
| – | Shakira feat. Wyclef Jean - Hips Don't Lie | 5 (1) |
| – | Lily Allen - Smile | 2 |
| – | McFly - Don't Stop Me Now / Please Please | 1 |
| – | Shakira feat. Wyclef Jean - Hips Don't Lie | 5 (4) |
| – | Beyonce feat. Jay-Z - Deja Vu | 1 |
| – | Justin Timberlake - Sexyback | 1 |
| – | Scissor Sisters - I Don't Feel Like Dancin' | 4 |
| – | Razorlight - America | 1 |
| – | My Chemical Romance - Welcome To The Black Parade | 2 |
| – | McFly - Star Girl | 1 |
| – | Fedde Le Grande - Put Your Hands Up 4 Detroit | 1 |
| – | Westlife - The Rose | 1 |
| – | Akon feat. Eminem - Smack That | 1 |
| – | Take That - Patience | 4 |
| – | Leona Lewis - A Moment Like This | 4 |
25 different songs hit number one in the UK during 2006.
