| Date | Artist - Title | Weeks at #1 |
|---|---|---|
1988 Number One Songs | ||
| – | Pet Shop Boys - Always On My Mind | 4 |
| – | Belinda Carlisle - Heaven Is A Place On Earth | 2 |
| – | Tiffany - I Think We're Alone Now | 3 |
| – | Kylie Minogue - I Should Be So Lucky | 5 |
| – | Aswad - Don't Turn Around | 2 |
| – | Pet Shop Boys - Heart | 3 |
| – | S'Express - Theme from S'Express | 2 |
| – | Fairground Attraction - Perfect | 1 |
| – | Wet Wet Wet / Billy Bragg - With A Little Help From My Friends / She's Leaving Home | 4 |
| – | Timelords - Doctorin' The Tardis | 1 |
| – | Bros - I Owe You Nothing | 2 |
| – | Glenn Medeiros - Nothing's Gonna Change My Love For You | 4 |
| – | Yazz and The Plastic Population - The Only Way Is Up | 5 |
| – | Phil Collins - A Groovy Kind Of Love | 2 |
| – | Hollies - He Ain't Heavy He's My Brother | 2 |
| – | U2 - Desire | 1 |
| – | Whitney Houston - One Moment In Time | 2 |
| – | Enya - Orinoco Flow (Sail Away) | 3 |
| – | Robin Beck - The First Time | 3 |
| – | Cliff Richard - Mistletoe and Wine | 4 |
20 different songs hit number one in the UK during 1988.
